Deep brain stimulation for treatment-resistant depression: a psychiatric perspective.
Identifieur interne : 002742 ( Main/Exploration ); précédent : 002741; suivant : 002743Deep brain stimulation for treatment-resistant depression: a psychiatric perspective.
Auteurs : Peter Giacobbe [Canada] ; Sidney H. KennedySource :
- Current psychiatry reports [ 1523-3812 ] ; 2006.
English descriptors
- KwdEn :
- Brain Mapping, Deep Brain Stimulation, Depressive Disorder, Major (physiopathology), Depressive Disorder, Major (therapy), Drug Resistance, Electroconvulsive Therapy, Electrodes, Implanted, Gyrus Cinguli (physiopathology), Humans, Internal Capsule (physiopathology), Nucleus Accumbens (physiopathology), Parkinson Disease (physiopathology), Parkinson Disease (therapy), Prognosis, Psychotherapy, Thalamus (physiopathology).
- MESH :
- physiopathology : Depressive Disorder, Major, Gyrus Cinguli, Internal Capsule, Nucleus Accumbens, Parkinson Disease, Thalamus.
- therapy : Depressive Disorder, Major, Parkinson Disease.
- Brain Mapping, Deep Brain Stimulation, Drug Resistance, Electroconvulsive Therapy, Electrodes, Implanted, Humans, Prognosis, Psychotherapy.
Abstract
Traditionally, the therapeutic approach to treatment-resistant depression (TRD) has relied on pharmacotherapy in various sequences and combinations, in addition to evidence-based psychotherapy or electroconvulsive therapy. Despite refinements to the existing therapeutic modalities, there remains a significant subpopulation of severely ill patients with refractory mood disorders who fail to achieve a clinical response despite aggressive psychosocial and biological treatments. Interest in the use of deep brain stimulation (DBS) for treatment-resistant psychiatric illness has emerged in recent years for a number of reasons: 1) as part of a general re-evaluation of both noninvasive and invasive brain stimulation techniques, 2) because of the demonstrated clinical efficacy of DBS for movement disorders, and 3) as a logical consequence of studies defining the functional neurocircuitry of several psychiatric disorders. This review will examine the progress of DBS in the treatment of Parkinson's disease and the potential implications for its use in TRD, as well as the role of the psychiatrist in selection and ongoing management of patients who receive this procedure.
PubMed: 17094923
Affiliations:
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Le document en format XML
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Kennedy</name></author></analytic><series><title level="j">Current psychiatry reports</title><idno type="ISSN">1523-3812</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain Mapping</term><term>Deep Brain Stimulation</term><term>Depressive Disorder, Major (physiopathology)</term><term>Depressive Disorder, Major (therapy)</term><term>Drug Resistance</term><term>Electroconvulsive Therapy</term><term>Electrodes, Implanted</term><term>Gyrus Cinguli (physiopathology)</term><term>Humans</term><term>Internal Capsule (physiopathology)</term><term>Nucleus Accumbens (physiopathology)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (therapy)</term><term>Prognosis</term><term>Psychotherapy</term><term>Thalamus (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Depressive Disorder, Major</term><term>Gyrus Cinguli</term><term>Internal Capsule</term><term>Nucleus Accumbens</term><term>Parkinson Disease</term><term>Thalamus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Depressive Disorder, Major</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Brain Mapping</term><term>Deep Brain Stimulation</term><term>Drug Resistance</term><term>Electroconvulsive Therapy</term><term>Electrodes, Implanted</term><term>Humans</term><term>Prognosis</term><term>Psychotherapy</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Traditionally, the therapeutic approach to treatment-resistant depression (TRD) has relied on pharmacotherapy in various sequences and combinations, in addition to evidence-based psychotherapy or electroconvulsive therapy. Despite refinements to the existing therapeutic modalities, there remains a significant subpopulation of severely ill patients with refractory mood disorders who fail to achieve a clinical response despite aggressive psychosocial and biological treatments. Interest in the use of deep brain stimulation (DBS) for treatment-resistant psychiatric illness has emerged in recent years for a number of reasons: 1) as part of a general re-evaluation of both noninvasive and invasive brain stimulation techniques, 2) because of the demonstrated clinical efficacy of DBS for movement disorders, and 3) as a logical consequence of studies defining the functional neurocircuitry of several psychiatric disorders. This review will examine the progress of DBS in the treatment of Parkinson's disease and the potential implications for its use in TRD, as well as the role of the psychiatrist in selection and ongoing management of patients who receive this procedure.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Kennedy, Sidney H" sort="Kennedy, Sidney H" uniqKey="Kennedy S" first="Sidney H" last="Kennedy">Sidney H. Kennedy</name></noCountry><country name="Canada"><noRegion><name sortKey="Giacobbe, Peter" sort="Giacobbe, Peter" uniqKey="Giacobbe P" first="Peter" last="Giacobbe">Peter Giacobbe</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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